CD256 (TNFSF13) is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. CD256 and its receptor are both found to be important for B cell development. In vitro experiments suggest that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM.

Recommended Applications WB, ICC   Applications and Recommended Dilution Factors   WB IHC ICC FC IP 1:1,000 - 10,000   1:100 - 250     Species Reactivity*   Human Mouse Rat Positive Positive Positive Species cross-reactivity based on Western blot analysis only Product Data   Western blot analysis on (A) Raji, (B) Jurkat, (C) HeLa, (D) PC-12, and (E) NIH/3T3 cell lysates using anti-CD256 RabMAb (cat. # 3115-1).   Specificity A synthetic peptide corresponding to residues in human CD256 was used as an immunogen. Storage Buffer & Conditions Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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1. Entrez Gene: gene-centered information at NCBI.

Nucleic Acids Res. 2005 Jan 1;33:D54-8.